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DeFeudis Professor of Biomedical Research University of Massachusetts Medical School Copyright 2015-2026 Linus Pauling Institute Disclaimer The Linus Pauling Institute's Micronutrient Information Center provides scientific information on the health aspects of dietary factors and supplements, food, and beverages for the general public

These pathogenic processes ultimately result in massive -cell loss and absolute insulin deficiency, thereby inducing dysregulation of glucose homeostasis (164)
The continued development of tophi results in destructive arthropathy (disease of a joint)
J Intern Med 2020;287:2235.

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