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Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder

Human umbilical vein endothelial cells (HUVEC, Lonza) were cultured in endothelial cell basal medium (EBM, Lonza) supplemented with endothelial cell growth medium (EGMSingleQuots, Lonza), 10% FBS, 2 mM L-glutamine, 100 U/mL penicillin and 100 g/mL streptomycin

This skin darkening (hyperpigmentation) is the result of exposure to the sun mixed with fluctuating hormones

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Constant scratching can lead to thickened, bleeding, or infected skin