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Cells were transfected with siRNA and then treated with 5.6 mM glucose or 25 mM glucose for 72 hours: A: siRNA enhanced cell proliferation under high glucose conditions B: siRNA decreased apoptosis under high glucose conditions

Combination of IGF-IR and RAF/MEK/Erk inhibitors may improve the efficacy in cancer therapy

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Cascinu S, Cordella L, ferro E et al