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In one B1 mechanism demonstrated in vitro, the electrophilic acetaldehyde attacks the C2 adjacent to the sulfur in the thiophene ring of B1, thereby lowering the bioavailability of B1

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doi: 10.2147/HIV.S14561 145 SpoonerLMOlinJL

Iron plays a critical role in redox reactions and mediates oxidative stress, which is considered a driving force in evolution [3]

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