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The activities of complex I [25, 26, 72, 73], complex I+III [21, 74] and complex IV [21, 26, 7278], and the content in cytochromes c and aa 3 [25] also were reported to decrease during aging
An Iranian meta-analysis (combination of many studies) showed that supplementing L-carnitine had no effect on physical performance
In addition to validating these experimental findings in different strains of mice, we also propose further exploration of multi-hit models in outbred colonies as they may more faithfully reflect the heterogeneous phenotypes and responses to therapy that are often seen in a diverse human population
(2021).Higgins JPTTJ, Chandler J, Cumpston M, Li T, Page MJ, Welch VA
