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Over transferrin bound (TBI) and non-transferrin bound iron (NTBI) can overwhelm the heavy chain ferritin (FtH) capacity, which lead to release of labile iron and render proximal tubular epithelial cells (PTEC) susceptible to iron oxidant damage, especial in distal tubular epithelial cells (DTEC) with lack iron storage (light and heavy chain ferritin) and export protein (ferroportin) (48)

As researchers follow published experimental precedents, so wrong values propagate and the noise-to-signal ratio within the literature increasingly confounds the development and testing of hypotheses

There is a link between bacterial metabolism, dietary choline intake, and cardiovascular risk (114)

Fierabracci P, et al
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