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The study authors found that intravenous injection of 42mg to 1260mg of TB4 was safe in healthy adults, with no dose limiting toxicities or serious adverse events reported [26]

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In published clinical trials, once weekly cagrilintide has been reported to produce dose dependent body weight reductions in participants with overweight or obesity, and it has also been studied in combination programmes with semaglutide, where trials reported greater weight loss than either component alone

The following points are essential to understand before interpreting the research data