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Pregnant and breastfeeding women: The requirement increases to 2.6 mcg per day

The discovery of vitamin B12 in the 1940s allowed veganism to become a realistic lifestyle

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Hydroxocobalamin and cyanocobalamin are commonly used forms for injections

In individuals with pre-existing gastrointestinal conditions such as inflammatory bowel disease, coeliac disease, or irritable bowel syndrome, introducing any new supplement may temporarily affect bowel habits as the digestive system adapts

Vitamin B12 is naturally present almost exclusively in animal-derived foods, making vegans and strict vegetarians particularly vulnerable unless they consume fortified foods or supplements