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The researchers went on to theorize that the downregulation of the HER-2/neu gene found in mammary adenocarcinoma is responsible for epitalons ability to inhibit the spontaneous production of mammary tumors in HER-2/neu mice ( Effects of Epitalon on Female Mouse Anatomy Epitalon is considered a strong antioxidant that could potentially be beneficial for longevity purposes

While this hasn't been extensively studied specifically for TB-500 receptors, the principle is well-established in pharmacology

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doi: 10.1016/0024-3205(92)90504-I

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