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Both PUFA-containing membrane PLs and free PUFAs can be peroxidized

10.21276/ujds.2020.6.3.6 Univ J Dent Sci

For instance, the interaction of MPO with neutrophil CD11b/CD18 integrins enhances tyrosine phosphorylation, leading to the activation of protein tyrosine kinases that are involved in the regulation of degranulation and neutrophil respiratory burst [314]

Kim S., Hwang S

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Of note, in the computational model, the loss of HMOX1, whose essentiality in the Fh1-deficient cells has been previously shown 8 , was expected to exacerbate the decreased ability of the FH-deficient cells to produce NADPH