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Therapeutic Perspectives and Challenges Although most therapeutic approaches put to test against LC have targeted symptom alleviation [307], a comprehensive evaluation of symptoms and clinical signs of affected patients is imperative, in order to timely recognize red flag features pointing towards underlying objective systemic disorders that are likely to have a decisive impact on patient prognosis

Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduces fasting triglycerides and enhances apolipoprotein A-V levels in non-diabetic subjects with hypertriglyceridemia

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Metabolic reprogramming is pivotal for tumorigenesis and progression, as tumor cells adapt to hypoxic and nutrient-deprived microenvironments by altering metabolic pathways to sustain rapid proliferation

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