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Molecular docking analyses suggested that compound 84 may bind with to the highly conserved hydrophobic pocket on the surface of the central trimeric coiled-coil of gp41

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Among the oxidative processes induced by PDT, LPO and MDA accumulation disrupt cellular homeostasis and trigger apoptotic pathways [139]

Targeted acquisition of eluting ions was performed in MRM mode with the following ion transitions: Q1 and Q3 ions at a full width at half maximum resolution of 0.7 m/z, an ion spray voltage of 2,500 V, CUR of 25 p

Downregulation of circ-BGN significantly increases the levels of lipid ROS, MDA, and Fe 2+ , inhibits GPX4 activity, and leads to the inhibition of activity in breast cancer cells (Wang et al., 2022a)

Delivered under appropriate clinical monitoring