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Zeigler DR

Cuproptosis Induced by ROS Responsive Nanoparticles with Elesclomol and Copper Combined with PD-L1 for Enhanced Cancer Immunotherapy

Dube, S

First, NK cells kill tumour cells by making direct contact with tumour cells that express specific ligands

In pro-oxidant conditions, two GSH molecules dimerize through a disulfide bond to form GSSG, whereas in antioxidant conditions GSSG is converted to GSH via NADPH-dependent glutathione reductase, as depicted in Figure 1 [2]

Erythrocytes were rinsed 3 times with cold 0.9% NaCl solution and hemolyzed by the addition of a 9-fold volume of cold phosphate-buffered saline (PBS) (50 mM, pH 7.4)