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Dihexa offers a mechanistically intriguing but unvalidated probe for HGF/c-Met neurobiology, with the critical caveat that its core published evidence is under question

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The peptide became widely recognized because of its specialized association with sleep-related biological signaling

J Biol Chem 279: 2593525938 Acknowledgements We thank The Wellcome Trust and the Biotechnology and Biological Sciences Research Council for financial support