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AOD-9604 holds FDA GRAS (Generally Recognized As Safe) status for food use a rare regulatory distinction among research peptides that reflects an established safety profile across multiple toxicology studies and chronic-exposure models

"Circadian regulation of NNMT expression and its role in metabolic homeostasis." Journal of Biological Rhythms, 36(4), 342-356

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doi: 10.2337/dc06-2375