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193 Furthermore, diazoxide inhibits glucagon secretion in healthy man 194 and in the dog, 195 but stimulates glucagon release in rats
This dual action, increasing fat breakdown while simultaneously reducing new fat formation, has been observed in multiple rodent adipocyte models and provides a mechanistically distinct experimental profile compared to compounds that affect only one arm of fat metabolism
References 1 BaillieGSTejedaGSKellyMP
2013;8:e74676
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