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Even more specifically, specific zonulin inhibition during the preclinical phase of arthritis by larazotide reduced the later development of arthritis by nearly 50%

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Schmidt EP, Yang Y, Janssen WJ, Gandjeva A, Perez MJ, Barthel L, Zemans RL, Bowman JC, Koyanagi DE, Yunt ZX, Smith LP, Cheng SS, Overdier KH, Thompson KR, Geraci MW, Douglas IS, Pearse DB, Tuder RM

Voetmann LM, Rolin B, Kirk RK, Pyke C, Hansen AK