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All published evidence is from animal or in vitro studiesno peer-reviewed human clinical trials have been completed as of 2026

Neuroprotective effect of CYP inducers was due to a decrease in ROS production, restoration of mitochondrial fusion kinetics, and mitochondrial membrane potential (Fernandez-Abascal et al., 2020)

Since post-translational control mechanisms have been proposed to participate in the regulation of rapid oxidative activation of GCL [15, 60], inducing ferroptosis by targeting PTMs might be a promising therapeutic strategy for cancer treatment

10.1016/j.juro.2010.10.048 J Urol

Mol Cell Biochem 479 , 27692784 (2024)

The scRNA-seq and CITE-seq data from colonic mucosal biopsies indicates that VDZ may play a role in attenuating MNP trafficking and activation, diminishing activation of inflammatory fibroblasts and endothelial cells, thus facilitating the recovery of intestinal epithelial cells