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Maintaining adequate intracellular glutathione concentrations is therefore a non-negotiable requirement for cellular survival, immune regulation, and systemic health

In this way, MSCs could promote repair through the production of anti-inflammatory cytokines such as interleukin (IL)-10 and TGF- 39 in addition to the inhibition of pro-inflammatory cytokines (tumor necrosis factor-, interferon gamma (IFN-), and IL-1 ), which have been identified to be released in the brains of PD patients 40,41

The activity of phosphatase PP2A in the hypoxia group decreased significantly (Fig