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10.1124/dmd.113.054254 17 SikiricP.RucmanR.TurkovicB.SeverM.KlicekR.RadicB.et al (2018)

Ideal candidates include individuals experiencing unexplained fatigue unresponsive to sleep and stress management, vegetarians and vegans lacking dietary B12 sources, adults over 50 with age-related absorption decline, patients with digestive disorders affecting nutrient absorption, those taking medications that deplete B12, and anyone seeking natural energy support without stimulants

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Optimizing flurbiprofen-loaded NLC by central composite factorial design for ocular delivery
