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183 The antimetastatic activity of Cu chelators may be attributed to their ability to prevent the recruitment of endothelial progenitor cells, which play an important role in angiogenesis and in the development of macroscopic metastases

[online] Clinical pharmacokinetics

404, 216220.10.1016/S0014-5793(97)00132-4 57 SchferH

M., Hirst, W

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The Randle cycle essentially describes that when fatty acid oxidation is active there is a significant reduction in the uptake and utilization of glucose by inhibition of PDH flux, but it also works the other way around, so the production of acetyl-CoA from glycolysis will inhibit fatty acid oxidation through the generation of malonyl-CoA which can inhibit CPT I [99]