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Stat Med

doi: 10.1016/j.lfs.2017.12.015

As a result, an increase in skeletal muscle total carnitine content may provide more effective buffering of acetyl-CoA production during high-intensity exercise, counteracting the increase in the acetyl-CoA/CoASH ratio and enhancing PDC flow and mitochondrial ATP production [23]

doi:10.1038/s41591-019-0590-4 Sage AP, Tsiantoulas D, Binder CJ, Mallat Z

Given the importance of fatty acids in muscle bioenergetics and the limiting influence of free carnitine on fatty-acid oxidation during endurance exercise, l-C supplementation has been proposed as a means of improving exercise performance [2]

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