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54 These proteins play multifaceted roles in microbial eradication, including promoting membrane permeabilization and lysis, exemplified by defensins and cathelicidins, and sequestering essential metals critical for microbial growth and enzymatic function, as seen with lactoferrin

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A comprehensive safety panel of relevant blood markers was quantified from each study subject at the beginning of the study, at 3 days after first dosing and after 2 weeks of GlyNAC consumption, including blood pressure, glucose, insulin, creatinine, Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), among others (Supplementary Table S3

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Hence, inhibition of HSC activation and its related events such as ECM formation and cellular proliferation are important targets for therapeutic intervention