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They are usually considered as the upstream diseases of T2D
Primary pathological findings are limited principally to these sites (sections 7 and 8)
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We have also shown that GH-induced insulin resistance is associated with suppressed pyruvate dehydrogenase activity in skeletal muscle (101)
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Because only a small share of patients with high B12 are found to have cancer, the value does not function as a standalone screening test
