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It has been broadly stated that mitochondrial DNA mutations, mitophagy, mitochondrial genesis and mitochondria-mediated apoptosis play a part in TC progression [303]

PD-L1 produced by HaCaT cells under polyinosinic-polycytidylic acid stimulation inhibits melanin production by B16F10 cells
Programmed cell death associated with autophagy Autophagy, derived from the Greek words auto meaning self and phagy meaning to eat, is a highly conserved cellular process that is essential for maintaining cellular health and homeostasis (Ohsumi, 2014)

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