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A separate, but similar study in depressed elderly patients also found that the treatment was effective in counteracting symptoms of depression in the elderly (Garzya 1990). In older patients with dysthymia, a more mild type of depression, acetyl-L-carnitine over the course of two months also proved helpful in reducing symptoms (Bella 1990)

Therefore, a novel intervention, PARTO, was recently developed

Among this limited research, the most frequently studied herbs seem to be those containing flavonoids or other polyphenols, plant compounds with significant antioxidant and anti-inflammatory properties

and C.H.P.) independently assessed the eligibility of each study

Funnel plot asymmetry and Eggers tests suggested potential small-study effects in some datasets (HDRS, BDI), raising concerns about publication bias

Source information: EMA 2013