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In practice, the usable capacity depends on the C-rate (discharge rate), temperature, and load conditions

Regardless of the continuously developing diagnosis and therapeutic approaches, heart failure has still a poor outcome with nearly 2550% mortality rate in 5 years after diagnosis 6

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The significance of PI3K activity in the regulation of PKB/AKT is evident from the fact that numerous PKB/AKT substrates are involved in the regulation of metabolism, cell growth, apoptosis, and autophagy