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Restoration of the NAD + levels by niacin, a NAD + precursor and B3 vitamin, provided health benefits, slowly reversing physical performance of some adult patients 15 .To find patients who have NAD + deficiency and could benefit from B3 treatment, we needed to set up validated technology and assess their values in the normal population

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This vasodilator increases the availability of inflammatory mediators (TNF-, L-selectin) which, at high concentrations, can damage epithelial cells and lead to bronchial contraction (101)