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Shimizu, T., Shimizu, S., Higashi, Y

Alterations in tryptophan metabolism affect vascular functions: connected to ageing population vulnerability to COVID-19 infection

Roughly 1 in 4 people with one autoimmune disease go on to develop additional autoimmune diseases

Neuroscience 94 , 937948 (1999)

doi: 10.3389/fmicb.2022.979719 Received 27 June 2022 Accepted 14 September 2022 Published 06 October 2022 Volume 13 - 2022 Edited by Wanbo Tai, Shenzhen Bay Laboratory, China Reviewed by Lihui Guo, University of Amsterdam, Netherlands

Glutathione synthesis is also supported by hepatic cysteine production via the transsulfuration pathway, which converts methionine to cysteine through homocysteine intermediates (7-8)