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Rogers R

Annu Rev Pharmacol Toxicol 2020;60:477502

EA can alleviate both macroscopic and microscopic colonic inflammation, upregulate the expression of claudin-1 and ZO-1 to repair the intestinal barrier, remold the overall structure of the gut microbiota, and inhibit pro-inflammatory factors IFN-, TNF-, and IL-6 through the MyD88-dependent TLR4 signaling pathway, preventing excessive immune response throughout the body (Liu et al., 2020)

Another approach uses nasal spray for maintenance phases after an initial injection loading phase

Some patients don't realize how depleted they felt until after starting supplementation

B12 Injections are now widely available and frequently requested, making expertise with their use highly valuable skills