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One major pathway involves insulin signaling through the phosphoinositide-3 kinase (PI3K)/protein kinase B (Akt) cascade, initiated by insulin receptor engagement

Acknowledgements We appreciate the participants and their families, and all academic personnel of the Al-Zahra Hospital, Isfahan, Iran for their kind cooperation

Eur J Nutr 52:16491659

203 Sugar and Calories Multiple studies have implicated high-sugar and high-calorie diets with the development of NAFLD
