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Our real-time oxygen consumption rate (OCR) measurement studies revealed reduced basal OCR, the sum of all physiological mitochondrial oxygen consumption, in an isolated mitochondria preparation from the hearts of METH-treated mice compared to those of the vehicle-treated group (Fig

10.1007/s12975-018-0672-5

10.3390/nu12051389 122 PicarielloF.FreemanJ.Moss-MorrisR

M.Merlo PichE

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As the NF-B expression is majorly dependent on the progressive expression of the TNF-, so the nuclear extracts were examined for NF-B pathway activation, and it was found that creatine significantly reduces the expression of the NF-B signaling pathway and alters anti-inflammatory responses [27]