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Amyotrophic Lateral Sclerosis (ALS) (Lou Gehrig's Disease) Amyotrophic Lateral Sclerosis (ALS) (Lou Gehrig's Disease) Last Section Update: 02/2019 Contributor(s) : Shayna Sandhaus, PhD 1 Overview Summary and Quick Facts for Amyotrophic Lateral Sclerosis (ALS) Amyotrophic lateral sclerosis (ALS) is a degenerative neuromuscular disease, also called Lou Gehrigs disease after the famous baseball player who died from this condition