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For decades, researchers have sought to develop a suitable in vivo AD model to study the pathological mechanisms of AD
These pollutants can harm sperm cells directly or cause systemic inflammation and oxidative stress in the male reproductive system
Deletion of the SOAR/CAD domain abolishes store depletion-induced clustering of Orai1 monomers and dramatically reduces SOCE, suggesting this domain is required for the assembly of the SOCE complex at ER-PM junctions (76, 77)
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