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Notably, lumateperone, an antagonist for D1, D2, D4, and serotonin receptor 2A and transporters (Kumar et al., 2018), improved depressive symptoms in bipolar depression patients in the first clinical trials (Calabrese et al., 2021), although it also showed potential inflammatory effects (El-Haroun et al., 2021)

Figueiredo HF, Ulrich-Lai YM, Choi DC, Herman JP

extract on mood, anxiety, stress, and cognition in moderately anxious students was evaluated

[DOI] [PubMed] [Google Scholar] Shen X.-M., Li H., Dryhurst G

A previously defined peptide derived from protachykinin-1 44 (TAC1), the gene which produces substance P and neurokinin A, and somatostatin (SST) were enriched in the resilient brain (Fig

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