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The most common side effects of Lexapro seen in clinical trials include: Headache Nausea Ejaculation problems Sleepiness Trouble sleeping Dry mouth Diarrhea Fatigue or tiredness Some other less serious side effects that may occur include: Dizziness Sweating Low appetite or weight loss (most commonly in children) Indigestion Constipation Lower sexual drive Flu-like symptoms Rarely, Lexapro may cause some more serious side effects such as: Serious, life-threatening allergic reactions

The T370A substitution has no significant effect on DAMGO-induced MOR internalization while it inhibits endocytosis triggered by PKC activation (Illing et al., 2014)

86 Sulforaphane was shown to improve bloodbrain barrier integrity, 87 reduce cerebral edema and improve cognition in a rodent model of TBI

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In practice, underdosing is common