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After 1 day of supplementation, AT-treated mice exhibited significantly higher Tkt mRNA levels than thiamine-treated mice, corresponding to an approximately 1.2-fold increase (Figure 10E)

This suggests that therapies targeting GPX4 could be particularly effective in melanomas resistant to apoptosis-inducing therapies, such as BRAF and MEK inhibitors [125]

However, for a long time, the consensus was that taking it as a standard pill was largely ineffective because the digestive system broke it down before it could reach the bloodstream

It interacts with free radicals to prevent cell damage and reduce the risk of cellular abnormalities, potentially leading to tumor formation

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