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Further, many reported small-molecule inhibitors target several metabolic enzymes with similar structures, for example, EGCG targets both NADPH-dependent FASN and NADP + -dependent GDH

doi: 10.1371/journal.pone.0228846 24 de Aguiar VallimT

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found that epithalon elongated telomeres and induced telomerase activity when introduced to telomerase-negative human fetal fibroblast cultures, with the authors concluding that epithalon may prolong the lifespan of cell populations [2]

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