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This just-formed superoxide, together with its reduced metabolites, can interact with a great number of different naturally occurring body biomolecules, at least partially leading to the development of many diseases such as cardiovascular disease, cancer, chronic inflammation, dementia, and amyotrophic lateral sclerosis, among others [140,141]

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For validation and sample analysis using the multiple standard addition approach, a series of spiking mixture solutions (low, medium, and high concentrations for validation, and adjusted concentrations for sample analysis) were prepared