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Because this element (henceforth referred to as the lid loop) is not highly conserved in sequence between LPLA2 and LCAT, it could play a role in determining their selectivity for N -acetylsphingosine (NAS) and cholesterol, respectively, as acyl acceptor substrates (see Discussion)

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10.1111/j.1365-2133.2011.10477.x [DOI] [PubMed] [Google Scholar] 20.Cochran AM, Buchanan PJ, Bueno RA, et al

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The AAHA publishes vaccine recommendations that are updated periodically to reflect the evolving knowledge of disease prevalence and vaccine effectiveness