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Glutathione peroxidase stands out among selenoproteins for male reproductive health due to its multiple redox processes and presence within mitochondrial membranes of spermatozoa as a regulatory mechanism, mitigating ROS production during motility [143]

Assessment of 8-hydroxy-guanosine (oh8G) as an indicator of oxidative DNA damage has displayed that ROS- induced DNA oxidation during the freezing procedures can be decreased after adding L-carnitine to the cryomedium (81)

therefore, modulations of K + -handling predominantly alter APD and the RMP (Schmitt et al., 2014

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