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In parallel, EAAT3 internalization activated by AMPH and closely-related compounds leads to an increase in extracellular glutamate and enhanced glutamatergic neurotransmission that also contributes to the behavioral outcomes of these drugs

Furthermore, GSH can modulate protein function via S-glutathionylation under oxidative stress

Lipids and cancer: emerging roles in pathogenesis, diagnosis and therapeutic intervention
Considering the putative role of oxidative stress as a pathogenetic factor for the development of colitis and because the reductive metabolism of TNBS has been shown to generate ROS, this model of colitis was chosen to evalute the temporal relationship between the levels of GSH in mucosa and the appearance and extent of injury in vivo during the acute phase of colitis in TNBS+ethanol-treated rats and to determine the effect of NAC administration on mucosal GSH levels and extent of injury
Vascular smooth muscle cells specific deletion of angiopoietin-like protein 8 prevents angiotensin II-promoted hypertension and cardiovascular hypertrophy

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