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Classically activated M1 microglia, induced by stimuli such as lipopolysaccharide (LPS) and interferon-gamma (IFN- ), release neurotoxic cytokines including IL-1 and tumor necrosis factor alpha (TNF- )

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The approach followed by Tan et al

Attacks can be prevented by proper nutrition and by avoiding the drugs that triggered the attack

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Unlike other drugs such as Mounjaro and Zepbound, which activate both GLP-1 and GIP receptors, MariTide works as a GLP-1 receptor agonist and a GIP receptor antagonist