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Given the link between GM and intestinal diseases, H 2 , particularly as an endogenous gas produced by GM, presents itself as a promising therapeutic agent

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Despite of various outcomes reported in vitro and in animal models, some studies are concentrated to humans and the results obtained are represented below in Table

3.3 AKK promotes epithelial migration and tight junction expression via p38 MAPK inhibition Having established the critical roles of both AKK and the p38 MAPK pathway in alleviating oxidative stress, we further examined their effects on the functional integrity of the intestinal barrier

High levels of the enzyme GGT detected has been an early forecast for development of a premature arteriosclerosis and other cardiovascular diseases, i.e