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Mercury can also directly accelerate the oxidative destruction of cell membranes and low-density lipoprotein (LDL) cholesterol particles as well as bind to and inactivate the cellular antioxidants N-acetyl cysteine, alpha-lipoic acid, and glutathione

The mutational features of aristolochic acid-induced mouse and human liver cancers

In hypoxic conditions, PP1s activity is suppressed, which leads to the overphosphorylation of CREB, followed by its ubiquitination and degradation by 26s proteasome

79 N-acetylcysteine (NAC) is a cysteine derivative with antioxidant and anti-inflammatory properties

Cancers (Basel) 15 (6), 1779

[254] reported that SF treatment reduced microglial activation and suppressed the production of pro-inflammatory cytokines such as TNF- and IL-6 in a mouse model of cerebral I/R injury