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Nature Reviews Cancer (2008) 9

This includes: Diluting the Vitamin B12 in a compatible IV solution Administering the infusion over a specified period, typically 30 minutes to an hour Monitoring the patient for any adverse reactions during and after the infusion By carefully considering these factors and following established guidelines, healthcare providers can optimize IV Vitamin B12 therapy for their patients

For adult males and females, they recommended 2.4 mcg/day, for pregnant females 2.6 mcg/day, and lactating females 2.8 mcg/day [5]

(2018) Oral vitamin B(12) versus intramuscular vitamin B(12) for vitamin B(12) deficiency

This observation seems to be confirmed by reported descriptions of cases of hypersensitivity to vitamin B12, which, mostly, document various types of skin reactions occurring at different times after intramuscular injection of this vitamin preparation [9,74,75,76,77]

Who Is Most Likely To Have Low Vitamin B12 Levels