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The animals were fed with a high-fat diet until 7-8 months of age and they were treated with MEM-supplemented water (30 mg/kg) during the last 12 weeks

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This approach has been especially useful for studying endometrial receptivity, where spatial organization is critical for function

Utilises the highly vascular nasal mucosa

Thus, for example, the two or three components mentioned above are made to occur in an ampule or vial by dissolving or suspending them in sterile water or sterile physiological saline

The mechanisms underlying their therapeutic efficacy are multifaceted, encompassing the competitive exclusion of pathogenic microorganisms from mucosal adhesion sites and the biosynthesis of antimicrobial metabolites that inhibit the proliferation of harmful microbes ( Table 3 Systemic therapeutic potential (oncology, gastroenterology, endocrinology (diabetes), cardiology, and neurology (gut-brain) of probiotics: a multi-disciplinary synthesis of mechanistic pathways and clinical efficacy