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Furthermore, GPx1-deficient hearts had decreased cardiac contractility and worse diastolic dysfunction in response to doxorubicin compared to wild type hearts [43]

Correcting low iron levels can alleviate fatigue and other symptoms

[DOI] [PubMed] [Google Scholar] 116.Hayes J.D., Dinkova-Kostova A.T., Tew K.D

doi: 10.1016/j.schres.2013.01.006

Many patients experience needle fatigue or outright refuse therapy, resulting in poor adherence and suboptimal clinical outcomes

While oliceridine is an effective analgesic, it has similar abuse liability to other opioid analgesics both in human and animal studies (Negus and Freeman, 2018)