l-carnitine and diabetes Carnitine dysregulation in diabetic kidney disease: from pathogenic mechanism to precision biomarker | Journal of Translational Medicine Insulin Resistance & Diabetes: Role
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The resultant accumulation of labile iron intensifies oxidative stress via Fenton chemistry and ultimately renders dopaminergic neurons highly susceptible to ferroptosis ( Cells export iron via the plasma membrane iron exporter protein, FPN1, the sole identified protein responsible for exporting intracellular iron in mammals (53)
Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of parkinsons disease
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HMGB1 signaling is induced via Receptor for advanced glycation endproducts (RAGE) and Toll-like receptors (TLRs), both of which are involved in DPN
R., Kutchma, A
The role of glutathione in cellular detoxification and antioxidant defense
