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Description
Clin Exp Optom
Due to defective renal absorption (free) carnitine is excreted in the urine of patients with primary deficiency and can result in tissue carnitine levels dropping to below 10% of normal [14, 22, 2426]
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The explanation for that could be due to the noticeable increase in oxidative stress in the testicular tissue, causing Leydig cell destruction
Effects of L-carnitine on arrhythmias during hemodialysis
however, it also involves sensors at the cellular and organelle level in the liver, pancreas, muscles, adipose tissues, and gut [30,31]
